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Question to answer: Discuss this post as far as how the research is being conducted. Propose an alternative method to doing the research in terms of method.   

If mixed methods was proposed discuss if what was proposed will be a good mixed methods study?  What can be added to make the study stronger?

If a qualitative study was proposed, discuss how the topic could studied using mixed methods.

If a quantitative  study was proposed, discuss how the topic could be studied using mixed methods.

 

What is the gap in the research you have identified from your attached review of the literature?

A gap in the research conducted is that the studies are all using a different type of antibiotic. Each study should use the same antibiotic and the dosage should be similar. This may be hard to accomplish since dosage is typically based on weight, so unless we have the patients around the same weight, it cannot always be one hundred percent equal.

Another gap in the research is that it is conducted on many different types of fractures. Maybe using one type of fracture like an open fracture where the bone has protruded through the skin, therefore having an increased chance for infection. This would allow the type of fracture most common to infections to be researched.

Another gap in research is the location. The research was conducted in many locations. They should make the research happen at the same location throughout a specific number of years.

What is a potential research question?

A potential research question based off the research studies in the literature review would be, “Does providing intravenous (IV) antibiotics during surgery decrease the incidence of surgical site infections (SSIs) in patients with fractures?”.

From the research questions, describe how you would go about conducting a research study.  I would go to an Orthopedic Surgery Center, where fractures are fixed most often, and would conduct research there. I would utilize the database to find all the patients that had surgery on an open fracture, since they have the highest potential for infection. I could conduct two different studies each year. The first could be solely observational and based off the outcomes (antibiotic usage, duration, type, etc.), I could make another study, a clinical trial, that would allow for use of the best outcome and make sure each individual patient is receiving that treatment. This would allow me to see numbers of how many patients are given the best quality of treatment they can be given. This study could be transferable and repeated many times if need be and can even be changed to trial and error based off antibiotic itself.
Would this be a qualitative, quantitative, or mixed methods research study? Discuss why you think this would be the best approach to the research question.

The test that would be solely observational would be qualitative and the clinical trial study would be quantitative, therefore creating a mixed methods study. This would be the best approach because it would allow me to see the difference in antibiotics, difference in duration, and difference in type of antibiotic, and would allow me to see what has worked best so far. This would allow me to make a clinical trial to see if the outcome was the same or very similar in most cases.

Talk about your sample and the procedure you would follow to recruit participants.

The only procedure I would follow would be an open fracture of a long bone. I want to use a minimum of 50 patients and a maximum of 100 patients for the observational study. More than 100 patients would be too many results to examine. For the clinical trial I could use up to 500 patients, that way it was completed before the next year and the next observational study.

 

Talk about any ethical issues that need to be considered.

A couple of the ethical issues that could arise would be informed consent, potential for harm, and confidentiality. Informed consent is important if the researchers do not want to be held liable for wrongful use of medical data. Harm could come about a patient in the clinical trials (which is another reason informed consent is needed). Confidentiality could be broken, and the name of the patient could be seen for more than just the researchers, which could create a HIPPA violation.

How would you go about collecting data?

I would use doctors’ notes, follow-up notes, procedural notes, patient surveys (I could have one for the day of the procedure and then again at the follow-up appointment in case the onset of infection is not right away).

What methods of data analysis might you use?

I could use a database or journaling to find which antibiotic provides the least rate of infection.

How long might this study take to conduct?

I would use one year for the study. I would conduct the qualitative, observational portion at first, and slowly conduct my quantitative, clinical trial portion. So, maybe three months of the qualitative portion and nine months of the quantitative portion. This study could be repeated for several years before compiling the final set of data, thus having an antibiotic that best aids in the reduction of a surgical site infection (SSI).

 

 

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HEALTH SCIENCE
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