solved
CASE 1
Martin James is a 73-year-old man who originally presented to the hospital with symptoms of heart failure that culminated in aortic and mitral valve replacement surgery. His surgery was complicated by a 1-hour hypotensive episode, with BP as low as 70/50. Three days post-operation, purulent drainage was noted from the surgical site, and he was subsequently diagnosed with mediastinitis. At that time, the patient was also found to have a Serratia bacteremia (blood cultures × 4 positive for Serratia marcescens, sensitive to gentamicin, piperacillin, ceftazidime, and ciprofloxacin; resistance was noted to ampicillin). Therapy was initiated with gentamicin and piperacillin. Thus far, he has completed day 25 of a 6-week course of antibiotics. A gradual increase in his BUN and serum creatinine concentration from baseline and signs of volume overload have been noted over the past 7 days (see Table below)
Martin has Type 1 DM, CKD, Gout, Osteoarthritis, HTN, and Atrial fibrillation. He has undergone Aortic and mitral valve replacement surgery 28 days ago. His father had Type 1 DM. He denies smoking or alcohol; he is a retired coal miner (11 years ago).
Current Medications: Gentamicin 180 mg IVPB Q 48 h (See Table below for previous dosages) Ceftazidime 1 g IVPB Q 12 h × 25 days Enalapril 5 mg po once daily Colace 100 mg po BID Furosemide 80 mg po Q 12 h × 2 days Digoxin 0.25 mg po once daily Allopurinol 100 mg po once daily Ranitidine 150 mg po Q 12 h Meperidine 25 mg IM Q 4-6 h PRN pain (started 3 days ago) Ibuprofen 400 mg po Q 4-6 h PRN pain (started today for joint pain) Sliding scale insulin
Allergies: Bactrim (experienced rash about 10 years ago; subsided when drug discontinued)
ROS: Currently complains of trouble breathing, weakness, general malaise, and pain in joints in hands. No fever or chills.
Physical Examination
Gen: Confused-appearing man in mild distress
VS: BP 152/90, P 80, RR 26, T 37.7°C; Current Wt 87 kg (admission Wt 73 kg), Ht 5’10”
Skin: Normal skin turgor
HEENT: PERRLA, EOMI, poor dentition
Neck/Lymph Nodes: (+) JVD
Chest: Basilar crackles, inspiratory wheezes
CV: S1, S2 normal, no S3, irregular rhythm
Abd: Soft, nontender, (+) BS, (-) HSM
Genit/Rect: (-) Masses
MS/Ext: 2+ Ankle/sacral edema
Neuro:A & O to person and place, but not to time
Lab Examination (Current)
UA: Color, yellow; character, hazy; glucose (-); ketones (-); SG 1.010; pH 5.0; protein 30 mg/dL; coarse granular casts 5-10/lpf; WBC 0-3/hpf; RBC 0-2/hpf; no bacteria; nitrite (-); osmolality 325 mOsm; urinary sodium 45 mEq/L; creatinine 33 mg/dL, FENA = 3.2%.
Repeat Blood Cultures Today Negative.
Fluid Intake/Output and Daily Weights
Question:
List down ACTIVE problems present. Rank them from the most urgent to the list urgent problem
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