1. Differentiate between the diagnostic criteria of

1. Differentiate between the diagnostic criteria of hypertension and isolated hypertension. 2. Joan is a 60-year-old Asian American patient who has been managed on Losartan 50mg PO daily, Amlodipine 10mg PO daily and HCTZ 25mg PO daily for the past 2 years. Although she is compliant with her prescribed antihypertensive and thiazide-diuretic medications, and follows a low-sodium diet, her systolic blood pressure remains in the 170’s, while her diastolic blood pressure averages around 85. Joan was recently diagnosed with Resistant hypertension. Discuss the pharmacological management of a patient, regarding resistant hypertension. (i.e.- What medication needs to be changed (if any)? What medication should to be added and why?) 3. Deena is a 55-year-old, obese African American female who presents with a blood pressure that averages around 160/90. Her primary care provider started her on Lisinopril 5mg PO daily, as a first-line therapy, which has not been effective. Based on Deena’s ethnicity, what class of antihypertensives would be first-line therapy and most effective for the management of hypertension and list the treatment plan that you would prescribe for her. 4. Donald is a 70-year-old patient, with no significant medical history, who has presented to the local clinic on 3 different days for blood pressure checks. His blood pressures were 139/90, 135/92, 140/85. Could Donald be diagnosed with hypertension (rationale)? If so, should he be started on medication at this time (rationale)?

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