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Introduction to Economic Evaluation of Health Promotion Interventions Homework 3 Evaluating Cost-effectiveness using Markov cohort models: The anorexia screening case The goal of this assignment is to provide students with applied practical experience using Markov cohort models to evaluate the cost-effectiveness of alternative decisions, in this case screening or not screening for anorexia in the school setting. The Markov cohort model included in this homework assignment is not intended to provide a realistic evaluation of the likely cost-effectiveness of each alternative given the limited nature of Markov cohort models and the artificial nature of a number of assumptions used to populate this model. Given the complexity of eating disorders epidemiology and transitions between eating disorder states, decision analysts have determined that microsimulation models will likely provide a better analytic strategy for comparing population health interventions. Be sure to review units 7.3 and 7.4 in the asynchronous materials before starting this assignment. This content is also covered well starting on page 331 in the Drummond textbook, continuing through page 335. Students will be provided with a diagram of the state transitions included in the model as well as the probabilities for transferring between states for each of the one-year model cycles. In contrast to the decision tree example from the previous homework assignment, students will be expected to use discounting to provide undiscounted and discounted health outcomes and costs for each of the alternative strategies in this homework. We will not be including half cycle correction. The cohort model described in this homework assignment will be run from the time that screening starts in time=0 to the end of Year 10. Assume that the discount rate is 3%. State Transition Diagram Image transcription text Model parameters needed for this assignment are: Transition Probabilities Intervention Transition To Healthy Early Severe Dead Total Transition From An… Show more Deliverables Completed Markov cohort model in Excel with calculated cost-effectiveness ratio in terms of cost per QALY both in discounted and undiscounted terms word commentary on the limitations of using the Markov cohort model in this case as well as the broader limitations of this modeling approach Grading Rubric You will receive 10 points (of total 15 for assignment) for a complete and accurate Excel Template, based on the following: 7 points for completed Markov model 1 points for accurate implementation of transition models 1 point for accurate definition of expected values 1 point for accurate discounting Guidance for methods write-up 3 points for completed write up 1 point for accurately summarizing general limitations of Markov cohort models 1 point for accurately summarizing limitations in this specific case
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