Image transcription text Parrato Estiles Q14. Identify one policy decision

Provide a simple and thorough explanation There is a short-acting version of this drug that’s used in the cath lab, and that particular agent binds to the thrombin only. We have a new drug class called the, “Direct antithrombin inhibitors.” These drugs are generally called, “NOACs,” because they stand for, “Novel Anticoagulant Drugs.” But because they’ve been on the market now for five or six years, we’ve kind of discarded the word, NOAC. Pradaxa or dabigatran is used as a twice daily drug, you can see that it’s much smaller than the heparin molecule, it’s approved for stroke prevention in atrial fibrillation, it’s also used for DVT prophylaxis, in post-op hip and knee surgery. The antidote called “Praxbind,” it is a monoclonal antibody. Let’s go to the old standby, “Warfarin.” Warfarin is the most commonly used drug in the entire lecture class. There are several derivatives that are used in Latin America and in the European Union, but in general warfarin is the most commonly used globally.

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