Case Study: A 28 year old female with bipolar II

Case Study: A 28 year old female with bipolar II disorder is prescribed antidepressants to treat her depressive episodes. The team is considering selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or atypical antidepressants such as bupropion. Research and answer: • Investigate the risk of antidepressant-induced mania in bipolar patients and how different classes of antidepressants (SSRIs like fluoxetine, SNRIs like venlafaxine, and atypical agents like bupropion) can trigger manic episodes. • Research the side effects common to each class (e.g., sexual dysfunction, insomnia with SSRIs, hypertension with SNRIs, and seizure risk with bupropion). • Review the teaching points for bipolar patients regarding the importance of combining antidepressants with mood stabilizers to prevent mania, and the need for close monitoring of mood changes during antidepressant therapy. • Compare how these antidepressants differ in their onset of action, common interactions, and safety profiles in patients with bipolar disorder.

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