A previously healthy adult female presents with dysuria, urinary urgency,

A previously healthy adult female presents with dysuria, urinary urgency, and frequency. She also reports right flank pain, fevers and chills, and nausea without vomiting. She has a decreased appetite but has been able to drink liquids. On examination, she has a temperature of 38.4°C (101.2°F), a heart rate of 102 beats/min, and a blood pressure of 126/82 mmHg. She has mild suprapubic tenderness and right costovertebral angle tenderness. A urinalysis shows microscopic pyuria, hematuria, and a positive leukocyte esterase test. Additional laboratory studies are notable for leukocytosis with a left shift but are otherwise normal, including a negative pregnancy test. The patient does not have allergies to any antibiotics. Which one of the following would be most appropriate for this patient? A. Outpatient management with oral amoxicillin (Amoxil) B. Outpatient management with oral ciprofloxacin (Cipro) C. Outpatient management with oral nitrofurantoin (Macrobid) D. Inpatient management with intravenous ceftriaxone (Rocephin)

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