Rosie, a 19 year old college student presents to the

Rosie, a 19 year old college student presents to the student health services for evaluation of abdominal pain. She has a history of Crohn’s disease with parital small bowel resection which has been managed well on natalizumab (Tysabri), a monoclonal antibody Her abdomen is distended, tender, and she describes frequent bloody stools. Based on her current presentation, what medication decisions are most appropriate at this time? Add adalimumab (Humira) to her natalizumab (Tysabri) No change is needed, continue on current dosing of natalizumab (Tysabri) Initiate prednisone (Deltasone) and maintain dosing of natalizumab (Tysabri) Stop natalizumab (Tysabri) as it is not safe during flare

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