A 38-year-old female with a past medical

A 38-year-old female with a past medical history of significant lupus erythematosus (SLE) and hypertension presents to her Primary Care Physician (PCP) for a wellness visit. On physical exam, she is in no distress, VS BP 160/80mmHg (normal takes metoprolol and lisinopril but forgets from time to time) HR 80bpm RR 20/min. Laboratory results show Hgb 14g/dl, WBC 5.0k, Platelets 160K, Cr. 1.80, eGFR 48ml/min. She denies fevers and chills. Denies diarrhea. The patient is concerned about her elevated Cr and asks the PCP a few questions. Q1: Compare the etiology of Acute and Chronic Kidney Disease. Q2: Describe the mechanism for Acute Kidney Injury in Acute Tubular Necrosis. Q3. Identify a nephrotoxin in the case study and discuss how it affects kidney function.

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