A 62-year-old man presents to primary care with bilateral lower

A 62-year-old man presents to primary care with bilateral lower leg pain that worsens with walking and is relieved by rest. He can walk two blocks before having to rest due to bilateral calf pain. His medical history includes diabetes and hypertension. He has a 30 pack-year smoking history. On physical examination, his dorsalis pedis pulses are weakly palpated bilaterally. Ankle-brachial indexes are performed: his right leg is 0.6, and his left leg is 0.8. The patient is counseled on strict management of lifestyle changes such as weight loss, smoking cessation, and tight control of his blood pressure and glycemic index. The patient returns for a 1-month follow-up without improvement. Which of the following medication regimens is appropriate to initiate at this time? A. Clopidogrel B. Aspirin C. Cilostazol D. Pentoxifylline E. Tirofiban

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