Michael, a 45-year-old man, has been struggling with severe asthma despite maximal therapy with high

Michael, a 45-year-old man, has been struggling with severe asthma despite maximal therapy with high-dose inhaled corticosteroids (ICS) and long-acting beta agonists (LABAs). His recent exacerbations have led to frequent emergency room visits and hospitalizations. After comprehensive evaluation, his pulmonologist determines that Michael’s asthma is refractory and predominantly driven by elevated levels of interleukin-5 (IL-5). Which of the following biologic agents would be the most appropriate treatment option for Michael’s condition? Group of answer choices Methylprednisolone Benralizumab Omalizumab Dupilumab

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