Paraphrase this: COPD is characterized by airflow limitation and chronic

Paraphrase this: COPD is characterized by airflow limitation and chronic respiratory symptoms, including cough and shortness of breath. It affects around 15 million people in the United States and costs more than $32 billion annually.1,2 Chronic lower respiratory tract diseases, including COPD, are the fourth leading cause of death in the United States and the third leading cause of death worldwide.3,4 Patients with COPD are at risk of acute exacerbations of symptoms resulting in the need for additional treatment. Acute exacerbations of COPD are generally characterized by increased dyspnea, increased frequency and severity of cough, and potentially increased sputum.5 Patients experiencing acute exacerbations of COPD are at increased risk of mortality and morbidity, lower quality of life, increased hospital admissions, and a progressive decline in lung function

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