Part 2: Critical Summary of Article 2

Part 2: Critical Summary of Article 2 (53 points) Carefully read Article #2: Lynch, F.L., Peterson, E., Lu, C.Y., Hu, Y., Rossom, R.C., Waitzfelder, B.E., et.al. (2020). Substance use disorders and risk of suicide in a general U.S. population: a case control study. Addition Science and Clinical Practice:15(14), https://doi.org/10.1186/s13722-020-0181-1 ( Please rely on the text, itself, rather than just the abstract. Then answer the following questions phrasing What is the purpose of this study? What are the main objectives? Do not rely solely on the abstract. Write the overall primary objective, and two secondary ones related to the major one. (4 points) What was the unit of analysis in this study? Was it on the group or individual level? 1 point.) What is the outcome variable of this study? (1 point) What are the exposure variables of this study? (3 points) What was the study design used here? (1 point) Explain why this is the study design mentioned in #5 (apart from the fact that the authors mention it by name). Which characteristics of this study make it that study design? (2 points) Where did the data for the study come from? (2 points) How many participants in each of the comparison groups were used in the analyses for this study? What was the ratio of the size of one comparison group to the other? (3 points) Describe the combined samples in detail by place and by time. (5 points) Based on how they got the samples, was there much of a possibility of selection bias in this study? Why or why not? When answering this , consider the following types of selection bias. Explain why each type of bias is or is not possible in this study. (6 points) Non-response Bias Loss to Follow-up Bias Healthy Worker Effect Hospital Admission Bias Exclusion Bias Prevalence Incidence Bias Focusing on the outcome variable of this study, how was the data for this outcome collected? Be sure to include the data set from which the information came, and if and how it was verified. (2 points) If some accidental overdose deaths were misclassified as suicides, would this overestimate or underestimate the number of suicides? Is it likely that the reverse occurred, that is, that there were suicides that nobody noticed? Why or why not? So in summary, was it possible that some misclassification of the outcome occurred? (4 points) SCIENCE HEALTH SCIENCE NURSING EPIDEMIOLO 613

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