Recordings from the lateral geniculate nucleus of

Recordings from the lateral geniculate nucleus of the thalamus illustrate that ion channels that cause INat, IK, and IL currents are present. These cells therefore fire both sodium and calcium spikes, such that strong depolarization causes a burst of action potentials, as depicted below (TTX eliminates the Na+ current, while nimodipine (Nim) eliminates the calcium current). Describe how these three currents are working in concert to produce the pattern illustrated below. In your answer comment on if you think these neurons have intrinsic oscillatory activity, like a pacemaker (i.e. they can fire without input stimulus), explain why or why not. SCIENCE HEALTH SCIENCE NURSING BIO 5595

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