Write a problem stated related to the occurrence of medication

Provide a simple and thorough explanation I have 1,200 patients on warfarin it’s a real headache, it’s one of the reasons why most doctors don’t like to use warfarin, because it’s so much work. The inhibitors of warfarin, which are listed here, reduce the clearance of warfarin and therefore the INR will climb, so, it’s really important knowing, that there are a lot of drugs that are going to interact with warfarin, as well as the antibiotics through a non-pharmacological pathway. Due to the multiple pharmacologic and non-pharmacologic interactions, and the narrow therapeutic index of warfarin, patients should regularly monitor the prothrombin time, “PT” and “INR.” When the INR is too high, there is increased risk of hemorrhage, and when it is too low, there is increased risk for thrombosis. The most specific antidote for warfarin toxicity is vitamin K, unfortunately, vitamin K takes several hours, in order to reverse the effects of warfarin.

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