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Question 21
Question text
CH 101
Match the terms about cancer with the correct description or fact.
Is due to the malignant cells being unresponsive to normal feedback mechanisms that regulate cell division
Answer 1
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Cancer cells can undergo endless divisions
Answer 2
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Can be slow or rapid, depending on the cells making up the neoplastic cells
Answer 3
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Cancer cells have the ability to break off from the site of origin and travel via the lymphatic and circulatory systems
Answer 4
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
This enzyme is active in most cancers and permits repeated division by preserving telomeres
Answer 5
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Secondary tumors that appear at sites distant from the primary tumor
Answer 6
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
These become progressively shorter with each cell division and normal cells then are unable to keep dividing
Answer 7
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Can penetrate adjacent tissues, allowing the spread of cancer
Answer 8
Choose.
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Unrestrained growth and division
Answer 9
Choose…
Persistent
proliferation
Telomeres
Metastases
Immortality
Invasive growth
Telomerase
Question 22
Question text
CH 101
Cytotoxic chemotherapy agents are most toxic to which of the following cells/tissues? (Select all that apply)
Select one or more:
a.
Liver cells
b.
GI epithelium
c.
Heart cells
d.
Neurons
e.
Bone marrow
f.
Sperm-forming cells
g.
Hair follicles
Question 23
Question text
CH 101
Chemotherapy can cause thrombocytopenia, which increases the risk of Answer
for the patient.
Question 24
Question text
CH 101
Most patients with cancer are treated with combination chemotherapy because it is generally more effective than using one drug.
Select one:
True
False
Question 25
Question text
CH 101
In the patient with neutropenia, typical signs of infection are often lacking, and Answer
is then the principal early sign of infection?
Question 26
Question text
CH 101
Match information about toxicity of chemotherapy with the correct terms
This occurs due to injury to the hair follicles and is a toxicity associated with the use of most cytotoxic anticancer drugs
Answer 1
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
Cooling of the scalp during administration of chemotherapy has been shown to decrease or prevent this
Answer 2
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
This toxicity is due to the damage that chemotherapy drugs, especially alkylating agents, can cause to DNA
Answer 3
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
Due to the effect on germinal epithelium, male patients should be counseled about
Answer 4
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
The major concern with this is injury to the kidneys
Answer 5
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
The developing fetus and the germinal epithelium of the testes are susceptible to chemotherapy because of their
Answer 6
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
These drugs can cause extensive tissue injury if they make direct contact with tissues
Answer 7
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
Usually begins 7-10 days after start of treatment and reverses about 1-2 months after treatment is completed
Answer 8
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
This can occur when chemotherapy causes a massive cell kill
Answer 9
Choose…
alopecia
high growth fraction
low growth fraction
Sperm banking
Carcinogenesis
Hyperuricemia
Vesicants
Question 27
Not yet answered
Question text
CH 101
True or False
Chemotherapy drugs are much more toxic to tissues that have a low growth fraction.
Select one:
True
False
Question 28
CH 101
When deciding whether to use chemotherapy for an individual patient with cancer, the patient care team can use the Answer ________________ ________________ to determine the general health status of the patient.
Question 29
CH 102
Which of the following is true about Cell-Cycle Phase-nonspecific drugs? (Select all that apply)
Select one or more:
a.Are more toxic to cells that are proliferating
b.
Are schedule dependent drugs
c.
Are more toxic to cells that are in the resting phase
d.
Increase cell kill when combined with phase-specific agents
e.
Can act during any phase of the cell cycle, including the resting phase
Question 30
Not yet answered
Points out of 1.00
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Question text
CH 101
Answer chemotherapy is the primary technique used to administer chemotherapy with the goal of producing 100% kill of neoplastic cells while limiting injury to normal tissues

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