Q1. Ethically the research nurse’s first duty

Q1. Ethically the research nurse’s first duty is to advocate for which group? Question 1 options: The benefit to the future. The medical physicians. The participating patients. The scientific researchers. Q2. Social sciences and behavioral research includes which of the following disciplines? Question 2 options: Educational. Economics. Psychology. All of the above. Q3. Which of the following group(s) display diminished autonomy and therefore should not give informed consent in research? Question 3 options: Minors. Mentally challenged children. Cognitively impaired elderly. All of the above. Q4. Ethically why can the researcher withhold treatment to the placebo group in a randomized control trial? Question 4 options: The interventional treatment is not known to be effective and efficacious. If the treatment exceeds expectations in the patients benefit the study can be stopped for benefit. The treatment is experimental and being tested for efficacy, effectiveness, and safety. All of the above. According to the Belmont Report on biomedical and behavioral practice which statement is accurate? Question 5 options: Research and practice may never be simultaneously conducted in practice. Adding any additional therapy to your practice necessitates research evaluation. If there are five or more new risky research elements included in practice, then research should be designed to evaluate safety and efficacy. Research and practice may be conducted simultaneously when research is designated to evaluate the safety and efficacy of a therapy in practice. Question 6 (Mandatory) (1 point) Which statement is an accurate definition of diminished autonomy? Question 6 options: Mental incompetence. Conscious patients. Non-terminal illness. Legal competence. Question 7 (Mandatory) (1 point) Which is the best definition of a Data Safety Monitoring Plan (DSMP)? Question 7 options: The National Institute of Health (NIH) and the NIH clinical trials committee demands that there will never be an unexpected or unanticipated result in the research study nor malfunction of devices. A Data Safety Monitoring Plan (DSMP) is not necessary if mortality and morbidity are end points of the study. A Data Safety Monitoring Plan (DSMP) is not indicated in clinical trials of new drugs or new devices. The National Institute of Health (NIH) and the NIH clinical trials committee mandate consideration of potential unexpected or unanticipated results and how they will be addressed by the researcher. Question 8 (Mandatory) (1 point) The Institutional Review Board (IRB) is currently Question 8 options: No longer necessary. Is not required by the FDA for human research. Remains in place due to violation of ethical principles. All of the above. Question 9 (Mandatory) (1 point) Which of the following is an example of research misconduct discovered in the Tuskegee Study of 1940? Question 9 options: Justice was violated by excluding certain subjects from participation. The right to Confidentiality and Privacy were violated by not protecting the identify of participant’s names and personal identification information. Fabrication of results and findings was research misconduct. The principle of Beneficence was violated by researchers withholding the new information that Penicillin was an effective treatment for syphilis. Question 10 (Mandatory) (1 point) Which of the following is an expected inclusion criterion demonstrating ethical treatment of children in research? Question 10 options: Permission denied by legal guardian(s). Permission denied by the parent(s). Obtaining assent from a child, if possible, as well as informed consent. Including all the potential sample population regardless of consent. Question 11 (Mandatory) (1 point) Consent rates are best explained by which of the following? Question 11 options: Percentage of subjects consenting to be included out of those approached. Percentage of total subjects approached for inclusion in the study. Percentage of participants dropping out of the study. Percentage of subjects remaining at end of the study. Question 12 (Mandatory) (1 point) Social sciences and behavioral research may involve improvement in the public health by focusing on which of the following? Question 12 options: Inherited diseases. Biomedical devices. Socio-economic or racial/ethnic health disparities. Surgically correcting genetic manipulations. Question 13 (Mandatory) (1 point) The four elements of consent according to Burns & Grove are disclosure, voluntariness, comprehension, and what? Question 13 options: Competency. Payment. Incompetency. Authorization. With an incompetent participant subject in research which is the best explanation of what must be included in their invitation into the study? Question 14 options: Subjects with diminished autonomy must have a written consent form signed by the subject, if able, as well as signed by the subject’s legally authorized representative. Subjects with diminished autonomy may not be included in any research study since they can not give voluntary consent. They would only be confused. Subjects with diminished autonomy must only be treated as a special study participant in a special, specific research study of their own. Subjects with diminished autonomy do not need to sign an informed consent, they must be included in the study to avoid discrimination. Question 15 (Mandatory) (1 point) The “Common Rule” covers which of the following? Question 15 options: The federal policy for the protection of human subjects in research. IRBs, informed consent, and assurances of compliance in research. Human research conducted/supported by federal department/agency. All of the above.

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