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Gentamicin is an aminoglycoside antibiotic which is
Gentamicin is an aminoglycoside antibiotic which is frequently used in the treatment of gram-negative bacilli infections. Since it is a low therpetuic index, it is important to determine proper doasgee regimens. In this study, patients on peritoneal dialysis received a 30 minute IV infusion of 80 mg gentamicin in 100 mL of 5% dextrose in water. Half-life is 16.1 hr and VD is 14.5 L. A patient is to be given gentamaicin by IV infusion. You wish to maintain a plasma concentration of 5.2 ug/mL. Determine the following: a)Find the plasma concentration if the infusion is discontinued at time=0.5 hr. b)Find the plasma concentration 2 hours after the infusion is discontinued at time =0.5 h
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