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Neoplasm and Genetic Disorders Guided Notes
List common roots and suffixes for tumors and state their meanings.
Compare and contrast the characteristics of a benign tumor and a malignant one.
How do tumors form?
How do tumors spread?
Why is there inflammation and infection at a tumor site?
What are warning signs of cancer?
How is cancer graded? What is the TNM staging of cancer?
What are local effects of tumors and how do they occur?
What are systemic effects of cancer and how do they occur?
Describe – adenoma, lipoma, fibrosarcoma, adenocarcinoma?
Which types of cancer have strong genetic links?
Describe the process of carcinogenesis.
What are some of the body’s defenses against cancer?
Describe the general types of cancer treatment options and how they work.
What is meant by prognosis, and what factors can impact it?
Review normal genetic makeup and patterns of inheritance.
Describe single gene disorder and give examples of this.
Describe autosomal recessive disorders and give examples.
Describe autosomal dominant disorders and give examples.
Describe X-linked dominant disorders and give examples.
Describe X-linked recessive disorders and give examples.
Describe chromosomal disorders and give common examples.
Describe multifactorial disorders and give examples.
What are developmental disorders, and what can cause them?
What are different ways of testing for genetic disorders?
What is genetic engineering?
How does gene therapy work?
What are:
Pedigrees
Karyotype
Genotype
What is the genetic pattern of hemophilia?
What is the genetic pattern of cystic fibrosis?
Down syndrome (trisomy 21)
Describe It Pattern of Inheritance Risk Factors Presentation/ Characteristics Diagnostic Measures
Klinefelter syndrome
Describe It Pattern of Inheritance Risk Factors Presentation/ Characteristics Diagnostic Measures
Turner syndrome
Describe It Pattern of Inheritance Risk Factors Presentation/ Characteristics Diagnostic Measures
Trisomy 18
Describe It Pattern of Inheritance Risk Factors Presentation/ Characteristics Diagnostic Measures
Diagnostic Tests
Test Name Test Description What Do the Findings Mean?
Amniocentesis
Cell-free DNA testing
PET scan

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