What changes does ageing have on the

What changes does ageing have on the kidneys and what does this increase the risk of? Select one: a. GFR increases with ageing, therefore larger doses are required as there is an increased risk of impaired therapeutic effect. b. GFR stays the same however the body metabolises medications differently due to increased water content of the body, monitoring of drug effect is required to avoid toxicity. c. The kidneys shrink therefore smaller, more frequent doses of medications are required to decrease rapid excretion. d. GFR decreases with ageing, decreasing drug excretion and increasing the risk of toxicity.

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