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Evidence of an association between a risk factor and a disease is not necessarily evidence of causation. Decisions about causation are important when planning interventions to alleviate the burden of disease in a population. Failure to target true causal mechanisms will limit the effectiveness of health care services.

Consider an example of research that reports an association between exposure to home dampness/mold and childhood allergic rhinitis. A reference for the journal article is provided below. Retrieve the full text of the article through the XU library.

 

Jaakkola, J. J. K., Hwang, B.-F., & Jaakkola, M. S. (2010). Home dampness and molds as determinants of allergic rhinitis in childhood: A 6-year, population-based cohort study. American Journal of Epidemiology, 172(4), 451-459. https://doi.org/10.1093/aje/kwq110

 

Use the guidelines for judging whether an observed association is causal to assess evidence of causation in this study.

These are the guidelines:

Case Studies in Causal Inference

As you review the research study, use this worksheet to make notes on whether there is evidence of causation between the risk factor and the disease. Refer to chapter 14 in your text for further information about the guidelines for judging whether an observed association is causal.

Temporal relationship

Strength of the association

Dose-response relationship

Replication of the findings

Biologic plausibility

Consideration of alternate explanations

Cessation of exposure

Consistency with other knowledge

Specificity of the association

 

Summarize your assessment of causation in an initial post to the discussion board (three hundred and fifty words).

SCIENCE
HEALTH SCIENCE
NURSING
NURS 864

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